Research Article

Aqueous Extract of Sorindeia Juglandifolia Leaves Protects Methotrexate-Induced Liver and Kidney Damage in Rat

Table 3

Effect of aqueous extract of Sorindeia juglandifolia on some serum parameters in kidney

Experimental group Urea (mg/dL) Creatinin (mg/dL) Calcium (mg/dL) Sodiummg/L Glomerular filtration (mL/24H)

Neutral control 9.46±0.82 0.23±0.01 11.00± 0.24 301,81±16,83 3.10-2±0.00

MTX control 32.46±1.35≠≠≠ 0.85±0.09≠≠≠ 10.67±0.23 169,67±13,34≠≠≠ 1.10-3±0.00≠≠≠

L-carnitin control 10.47±1.32αα 0.36±0.02αα 11.4±0.25 352,89±12,09ααα 2.10-2±0.00≠ααα

S.jug 150 mg/kg 28.46±5.50≠≠≠* 0.58±0.02≠≠≠** 11.27±0.25 357,44±15,74ααα 1.10-2±0.00≠≠≠*

S.jug 250 mg/kg 13.67±0.82α 0.37±0.02αα 10.91±0.22 346,01±9,10ααα 2.10-2±0.00≠≠≠αα

S.jug 350 mg/kg 16.07±0.82α 0.38±0.04α 10.68±0.24 337,38±25,52ααα 1.10-2±0.00≠≠≠α