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Keywords = psychosis

  • Open Access Research Article
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    Trends Journal of Sciences Research 2018, 3(3), 133-137. http://doi.org/10.31586/Psychiatry.0303.05
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    Abstract
    Objective: Suicide is the most common cause of premature death of schizophrenia. This study investigated the relationship between cholesterol levels and suicidal behaviour in chronic psychosis. Methods: The study group consisted of 109 schizophrenia, schizoaffective and other non affectice psychosis defined by Diagnostic and Statistical Manual of Mental Disorders, 5th
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    Objective: Suicide is the most common cause of premature death of schizophrenia. This study investigated the relationship between cholesterol levels and suicidal behaviour in chronic psychosis. Methods: The study group consisted of 109 schizophrenia, schizoaffective and other non affectice psychosis defined by Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-V) criteria. Lifetime suicide attempts of patients were retrospectively screened. The patients were divided into two groups with and without suicide. Serum cholesterol levels were compared between two groups. Results: The mean total cholesterol, triglyceride, HDL and LDL levels were 163.8 mg/dl,150.8 mg/dl,40.8 mg/dl and 132.4 mg/dl, respectively in the study group while they were 197.1 mg/dl, 194 mg/dl, 44.9 mg/dl and 124.2 mg/dl, respectively in the control group. Total cholesterol levels were significantly lower than patients with suicidal attempts compared with the patients with no suicidal attemps (p=0,03). No association was found between suicidal attempt and HDL cholesterol (p=0,24), triglyceride (p=0,193), and LDL(p=0,45). Conclusion: This result supports the hypothesis of association low plasma cholesterol levels and suicidal behavior in psychosis  Full article
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