View options
Result details

Results per page
Articles per page View Sort by

2 results for Genes

  • Open Access Research Article
    Export citation: APA   BibTeX   EndNote   RIS  
    Trends Journal of Sciences Research 2018, 3(2), 69-74. http://doi.org/10.31586/Physiology.0302.02
    47 Views 7 Downloads 3 Shares PDF Full-text (2.323 MB)  HTML Full-text
    Abstract
    Heat stress can affect reproduction potential as an environmental factor. This Study was carried out to investigate the effects of rosemary extract on spermatogenesis and sexual hormones of laboratory mice under heat stress. 50 male mature mice were examined in five groups including a control group and four experimental groups
    [...] Read more.
    Heat stress can affect reproduction potential as an environmental factor. This Study was carried out to investigate the effects of rosemary extract on spermatogenesis and sexual hormones of laboratory mice under heat stress. 50 male mature mice were examined in five groups including a control group and four experimental groups [0, 100, 200 and 400 mg/kg of rosemary extract]. Samples were kept under heat stress four hours a day and received the extract doses for 30 days. At the end of the experiment, the amount of testosterone, LH, and FSH hormones plus the number of spermatogenic cells were measured. Obtained data were analyzed using the SPSS program. Heat stress in zero doses reduced testosterone, LH, and FSH significantly whereas rosemary extract increased testosterone and LH in 200 and 400 doses and FSH in 100,200, and 400 doses. Primary spermatocytes were decreased in zero doses significantly but increased significantly in other experimental groups [p<0.05]. In general, Heat stress reduces male sex hormones and spermatogenic cells but rosemary extract compensated this reduction dose-dependently and improved sexual potential under heat stress.  Full article
    Figures

    Figure 1 of 4

    References
    [1]
    Gayton A. 2011. Medical physiology (Translated by Farrukh Shadan), Tehran University. 2, 245.
    [2]
    Collier RJ, Dahl GE, Van Baali MJ. 2006. Major advances associated with environmental effects on dairy cattle. J Dairy Sci. 89, 1244-53.
    [3]
    Premkumar K, Abraham SK, Santhiya ST, Ramesh A. 2003. Protective effects of saffron (Crocus sativus L.) on genotoxin-induced oxidative stress in Swiss albini mice Phytother Research. 17, 614-17.
    [4]
    Modaresi M. 2012. A comparative analysis of the effects of garlic, elderberry and black seed extract on the immune system in mice. J Anim Vet Adv. 11 (4), 458-61.
    [5]
    Ojeda-sana A M, Van baren C M, Elechosa M A, Juarez M A, Morenos S. 2013. New insights into antibacterial and antioxidant activities of rosemary essential oils and their main components. Food Control. 31(1), 189–195.
    [6]
    Posadas S, Caz V, Largo C, De La Gandara B, Matallans B, Reglero G. et al. 2009. Protective effect of supercritical fluid rosemary extract, Rosmarinus officinalis, on antioxidants of major organs of aged rats. Experimental gerontology. 44(6), 383–389.
    [7]
    Modaresi M, Mohajer M. 2015. The Effect of Garlic Extract on Spermatogenesis and Sexual Hormones in Heat-Stressed Male Mice. zumsj. 23 (101), 88-97.
    [8]
    Ghiasi Ghalehkandi J. 2014. Garlic (Allium sativum) juice protects from semen oxidative stress in male rats exposed to chromium chloride. Anim Reprod. 15, 526-32.
    [9]
    Arts M J, Haenen G R, Voss H P, Bast A. 2001. Masking of antioxidant capacity by the interaction of flavonoids with protein. Food and Chemical Toxicology. 39(8), 787–791.
    [10]
    Satoh T, Kosaka K, Itoh K, Kobayashi A, Yamamoto M, Shimojo Y. et al. 2008. Carnosic acid,a catechol?type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S?alkylation of targeted cysteines on Keap1. Journal of neurochemistry. 104(4), 1116–1131.
    [11]
    Satoh T, Izumi M, Inukai Y, Tsutsumi Y, Nakayama N, Kosaka Kosaka. et al. 2008. Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid-and catechol hydroxyl moieties-dependent manners. Neuroscience letters. 434(3), 260–265.
    [12]
    Jasim MA, Al-Tahan FJ. 2012. Study of the effect of decorticated and defatted castor seeds (Ricinus communis Linn.) on testosterone level and testicular architecture of male mice. J Tikrit University of Agriculture Sci. 12,176-80.
    [13]
    Kaur R, Kaur K. 2000. Effects of dietary selenium (SE) on morphology of testis and cauda epididymis in rats. Indian J Physiol Pharmacol. 44, 265-72.
  • Open Access Mini Review
    Export citation: APA   BibTeX   EndNote   RIS  
    Trends Journal of Sciences Research 2018, 3(2), 75-81. http://doi.org/10.31586/Nursing.0302.03
    31 Views 19 Downloads PDF Full-text (2.583 MB)  HTML Full-text
    Abstract
    Genotype and lifestyle factors have been implicated as the causes of non-communicable diseases including diabetes, cardiovascular diseases, cancer and chronic respiratory disease. Lifestyle factors constitute physical activity, smoking, alcohol intake and dietary habits. These factors alongside genetic factors have been studied over the past years on their relationships with non-communicable
    [...] Read more.
    Genotype and lifestyle factors have been implicated as the causes of non-communicable diseases including diabetes, cardiovascular diseases, cancer and chronic respiratory disease. Lifestyle factors constitute physical activity, smoking, alcohol intake and dietary habits. These factors alongside genetic factors have been studied over the past years on their relationships with non-communicable diseases. This review examined and compared the strengths of the two factors, lifestyle and genotype, in causing non-communicable diseases. A search was done online, predominantly with PubMed, to identify articles that contained the keywords, lifestyle, diet, exercise, genotype, gene, non-communicable diseases, cardiovascular diseases, cancer, chronic respiratory disease, diabetes. For diabetes, the results of this review showed that management of lifestyle factors can be used to prevent type 2 diabetes among genetically predisposed persons. Cancers studies have suggested that a Mediterranean diet is associated with lower cancer risk for both genetically susceptible people and non-susceptible individuals. Similar findings were gotten for cardiovascular diseases and chronic respiratory diseases. The results suggest a strong impact of lifestyle-related factors as a cause of non-communicable diseases though genetic factors cannot be underestimated. With good management of lifestyle factors, non-communicable diseases can be prevented and the risks reduced even among genetically high-risk individuals.  Full article
    References
    [1]
    World Health Organisation, Global action plan for the prevention and control of non-communicable diseases 2013-2020. Available at: who.int/iris/bitstream/10665/94384/1/9789241506236_eng.pdf. 2013. Accessed March 22, 2017.
    [2]
    Melaku YA, Temesgen AM, Deribew A, Tessema GA, Deribe K, Sahle BW, et al. The impact of dietary risk factors on the burden of non-communicable diseases in Ethiopia: findings from the Global Burden of Disease study 2013. International Journal of Behavioral Nutrition and Physical Activity 13 (2016) 122-134.
    [3]
    Hosseini-Esfahani F, Mirmiran P, Daneshpour MS, Mottaghi A, Aziz F. The effect of interactions of Single Nucleotide Polymorphisms of APOA1/APOC3 with food group intakes on the risk of metabolic syndrome. Avicenna J Med Biotech 9 (2017) 94-103.
    [4]
    Chikwere P, Annan RA. Dietary habit and other lifestyles and serum lipid profile of type 2 diabetes patients: a systematic review. Nutrition & Food Science 46 (2016) 161-170.
    [5]
    Chikwere P, Nsiah K, Tandoh MA. Relation of unsupported and unsupervised exercise with anthropometric and biochemical indices among type 2 diabetic patients. Turk J Med Sci 47 (2017) 85-90.
    [6]
    Naicker A, Venter CS, MacIntyre, UE, Ellis S. Dietary quality and patterns and non-communicable disease risk of an Indian community in KwaZulu-Natal. South Africa Journal of Health, Population and Nutrition 33 (2015) 12-20.
    [7]
    Chikwere P, Nsiah K, Tandoh MA, Agyenim-Boateng K. The relation of dietary pattern to serum lipid profile and uric acid among type 2 diabetes patients. J. Nutr. Ecol. Food Res 2 (2014) 207-213.
    [8]
    Neel JV. Diabetes mellitus: a ‘‘thrifty’’ genotype rendered detrimental by ‘‘progress’’? Am J Hum Genet 14 (1962) 353-362.
    [9]
    Langenberg C, Sharp S, Forouhi NG, Franks P, Schulze MB, Kerrison N, et al. The InterAct Project: An Examination of the Interaction of Genetic and Lifestyle Factors on the Incidence of Type 2 Diabetes in the EPIC Study. Diabetologia 54 (2011) 2272-2282.
    [10]
    Langenberg C, Sharp SJ, Franks PW, Scott RA, Deloukas P, Forouhi NG, et al. Gene-lifestyle interaction and type 2 diabetes: The EPIC InterAct case-cohort study. PLoS Med 11 (2014) e1001647.
    [11]
    Walker CG, Solis-Trapala I, Holzapfe C, Ambrosini GL, Fuller NR, Loos RJF, et al. Modelling the interplay between lifestyle factors and genetic predisposition on markers of type2 diabetes mellitus risk. PLoS ONE 10 (2015) e0131681.
    [12]
    Phillips CM. Nutrigenetics and metabolic disease: current status and implications for personalised nutrition. Nutrients 5 (2013) 32-57.
    [13]
    Hivert M, Jablonski KA, Perreault, L. Updated genetic score based on 34 con?rmed type 2 diabetes loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program. Diabetes 60 (2011) 1340-1348.
    [14]
    Chikwere P. Functional foods and nutraceuticals, wonders in cancer risks - a review. World Scientific News 64 (2017) 18-33.
    [15]
    Buckland G, Agudo A, Luján L, Jakszyn P, Bueno-de-Mesquita H, Palli D, et al. Adherence to a Mediterranean diet and risk of gastric adenocarcinoma within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study. Am J Clin Nutr 91 (2010) 381-390.
    [16]
    Ibáñez-Sanz G, Díez-Villanueva A, Henar Alonso M, Rodríguez-Moranta F, Pérez-Gómez B, Bustamante M, et al. Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study. Scientific Reports 7 (2017) 43263.
    [17]
    Stein B, Anderson JC, Rajapakse R, Alpern ZA, Messina CR, Walker G. Body mass index as a predictor of colorectal neoplasia in ethnically diverse screening population. Dig Dis Sci 55 (2010) 2945-2952.
    [18]
    Abulí A, Fernández-Rozadilla C, Alonso-Espinaco V, Muñoz J, Gonzalo V, Bessa X, et al. Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins. BMC Cancer 11 (2011) 339-346.
    [19]
    Huo D, Zheng Y, Ogundiran TO, Adebamowo C, Nathanson KL, Domchek SM, et al. Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry. Carcinogenesis 33 (2012) 835–840.
    [20]
    Ko K-P, Kim S-W, Ma SH, Park B, Ahn Y, Lee JW, et al. Dietary intake and breast cancer among carriers and noncarriers of BRCA mutations in the Korean Hereditary Breast Cancer Study. Am J Clin Nutr 98 (2013) 1493-1501.
    [21]
    Toledo E, Salas-Salvadó J, Donat-Vargas C, Buil-Cosiales P, Estruch R, Ros E, et al. Mediterranean Diet and Invasive Breast Cancer Risk Among Women at High Cardiovascular Risk in the PREDIMED Trial: A Randomized Clinical Trial. JAMA Intern Med 175 (2015) 1752-1760.
    [22]
    Sanchez NF, Stierman B, Saab S, Mahajan D, Yeung H, Francois F. Physical activity reduces risk for polyps in a multiethnic colorectal cancer screening population. BMC Research Notes 5 (2012) 312-319.
    [23]
    Folkersen L, van’t Hooft F, Chernogubova E, Agardh HE, Hansson GK, Hedin U. Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease. Circ Cardiovasc Genet 3 (2010) 365-373.
    [24]
    Sotos-Prieto M, Baylin A, Campos H, Qi L, Mattei J. Lifestyle Cardiovascular Risk Score, Genetic Risk Score, and Myocardial Infarction in Hispanic/Latino Adults Living in Costa Rica. J Am Heart Assoc 5 (2016) e004067.
    [25]
    Corella D, Asensio EM, Coltell O, Sorlí, J. V., Estruch, R., Martinez-González, M.A, et al. CLOCK gene variation is associated with incidence of type 2 diabetes and cardiovascular diseases in type 2 diabetic subjects: dietary modulation in the PREDIMED randomized trial. Cardiovascular Diabetology 15 (2016) 4-15.
    [26]
    Garg V, Muth AN, Ransom JF, Schluterman MK, Barnes R, King IN, et al. Mutation in NOTCH1 cause aortic valve disease. Nature 437 (2005) 270-274.
    [27]
    Khera AV, Emdin CA, Drake I. Genetic risk, adherence to a healthy lifestyle, and coronary disease. N Engl J Med 375 (2016) 2349-2358.
    [28]
    Micha R, Peñalvo JL, Cudhea F, Imamura F, Rehm CD, Mozaffarian D. Association between dietary factors and mortality from heart disease, stroke, and type 2 diabetes in the United States. JAMA 317 (2017) 912-924.
    [29]
    Estruch R, Ros E, Salas-Salvadó J. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 368 (2013) 1279-1290.
    [30]
    McKeever TM, Lewis SA, Cassano PA, Ocké M, Burney P, Britton J, Smit HA, et al. Patterns of dietary intake and relation to respiratory disease, forced expiratory volume in 1 s, and decline in 5-y forced expiratory volume. Am J Clin Nutr 92 (2010) 408-415.
    [31]
    Powell R, Davidson D, Divers J, Manichaikul A, Jeffrey Carr J, Detrano R, et al. Genetic ancestry and the relationship of cigarette smoking to lung function and per cent emphysema in four race/ethnic groups: a cross-sectional study. Thorax 68 (2013) 634-642.
    [32]
    Sorli-Aguilar M, Martin-Lujan F, Flores-Mateo G, Arija-Val V, Basora-Gallisa J, Sola-Alberich R. Dietary patterns are associated with lung function among Spanish smokers without respiratory disease. BMC Pulmonary Medicine 16 (2016) 162-173.
    [33]
    Sabater-Lleal M, Mälarstig A, Folkersen L, Artigas MS, Baldassarre D, Kavousi M, Almgren P, et al. Common Genetic Determinants of Lung Function, Subclinical Atherosclerosis and Risk of Coronary Artery Disease. PLoS ONE 9 (2014) e104082.
Filter options
Publication Date
From to
Refine Publication Date
Subject Areas
Refine Subjects
Article Types
Refine Article Types
Countries / Territories
Refine Countries / Territories