Research Article | Open Access | 10.31586/Psychiatry.0303.05

Relationship between Cholesterol Levels and Suicide Attempts in Chronic Psychosis

Cholesterol Levels and Suicide Attempts in Chronic Psychosis

  • Ahmet Ziya Sahin1,*, Sengul Sahin2 and Sakir Ozgur Keskek3
    1
    Department of Internal Medicine, Cukurova State Hospital, Turkey
    2
    Department of Medical Faculty, Gaziantep University, Turkey
    3
    Department of Internal Medicine, Adana Rerearch and Training Hospital, Turkey

Abstract

Objective:


Suicide is the most common cause of premature death of schizophrenia. This study investigated the relationship between cholesterol levels and suicidal behaviour in chronic psychosis


Methods:


The study group consisted of 109 schizophrenia, schizoaffective and other non affectice psychosis defined by Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-V) criteria. Lifetime suicide attempts of patients were retrospectively screened. The patients were divided into two groups with and without suicide. Serum cholesterol levels were compared between two groups. Results:The mean total cholesterol, triglyceride, HDL and LDL levels were 163.8 mg /dl,150.8 mg /dl,40.8 mg /dl and 132.4 mg/dl, respectively in the study group while they were 197.1 mg / dl, 194 mg / dl, 44.9 mg / dl and 124.2 mg/dl, respectively in the control group. Total cholesterol levels were significantly lower than patients with suicidal attempts compared with the patients with no suicidal attemps (p=0,03). No association was found between  suicidal attempt and HDL cholesterol (p=0,24), triglyceride (p=0,193), and LDL(p=0,45).  Conclusion:This result supports the hypothesis of association low plasma cholesterol levels and suicidal behavior in psychosis

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Published
October 10, 2018
How to Cite
SAHIN, Ahmet Ziya; SAHIN, Sengul; KESKEK, Sakir Ozgur. Relationship between Cholesterol Levels and Suicide Attempts in Chronic Psychosis. Trends Journal of Sciences Research, [S.l.], v. 3, n. 3, p. 133-137, oct. 2018. ISSN 2377-8083. Available at: <http://tjsr.org/journal/index.php/tjsr/article/view/73>. Date accessed: 21 oct. 2018.
Section
Psychiatry