Research Article | Open Access | 10.31586/Nanomaterials.0303.03

Nanoceramics in Bone Tissue Engineering: The Future Lies Ahead

  • Zorawar Singh Department of Zoology, Khalsa College, India


Nanoceramics are composed of ceramics and are classified as inorganic, heat-resistant, nonmetallic solids made of both metallic and nonmetallic compounds. Bone tissue engineering applies bioactive scaffolds, host cells and osteogenic signals for restoring damaged or diseased tissues. Composites of bioactive ceramics closely match the properties of bone. In the present review paper, an attempt has been made to emphasize the suitability of nanoceramics in the field of bone tissue engineering. Toxicity of these synthesized nanomaterials should be checked before their real application. Nanoceramics, in future, will surely prove to be important nanomaterials in the field of tissue engineering.


Figure 1 of 1


Kiani, A., Rahmani, M., Manickam, S. & Tan, B. Nanoceramics: Synthesis, characterization, and applications. J. Nanomater. 2014, 2?4 (2014).
Bagchi, A., Meka, S. R., Rao, B. N. & Chatterjee, K. Perovskite ceramic nanoparticles in polymer composites for augmenting bone tissue regeneration. Nanotechnology. 25, 485101 (2014).
Sethu, S. N. et al. Nanoceramics on osteoblast proliferation and differentiation in bone tissue engineering. Int.J.Biol.Macromol. 98, 67?74 (2017).
Amini, A. R., Laurencin, C. T. & Nukavarapu, S. P. Bone tissue engineering: recent advances and challenges. Crit. Rev. Biomed. Eng. 40, 363?408 (2012).
Nanoceramics (Nanotechnology). Available at:
Itoh, H., Wakisaka, Y., Ohnuma, Y. & Kuboki, Y. A new porous hydroxyapatite ceramic prepared by cold isostatic pressing and sintering synthesized flaky powder. Dent.Mater.J. 13, 25?35 (1994).
Yao, Z., Tan, S., Xia, M., Ye, Y. & Li, J. Synthesis, characterization and sintering behaviour of indialite ceramic from fly ash. Waste Manag. 29, 1090?1097 (2011).
Denry, I., Goudouri, O. M., Harless, J. & Holloway, J. A. Rapid vacuum sintering: A novel technique for fabricating fluorapatite ceramic scaffolds for bone tissue engineering. J.Biomed.Mater.Res.B Appl.Biomater. 106, 291?299 (2018).
Goodridge, R. D., Dalgarno, K. W. & Wood, D. J. Indirect selective laser sintering of an apatite-mullite glass-ceramic for potential use in bone replacement applications. Proc.Inst.Mech.Eng H. 220, 57?68 (2006).
Dinesh, K. S. et al. Formulation and biological actions of nano-bioglass ceramic particles doped with Calcarea phosphorica for bone tissue engineering. Mater.Sci.Eng C.Mater.Biol.Appl. 83, 202?209 (2018).
Rezaei, M. et al. Nano-Biphasic Calcium Phosphate Ceramic for the Repair of Bone Defects. J.Craniofac.Surg. (2018).
Deepthi, S., Venkatesan, J., Kim, S. K., Bumgardner, J. D. & Jayakumar, R. An overview of chitin or chitosan/nano ceramic composite scaffolds for bone tissue engineering. Int.J.Biol.Macromol. 93, 1338?1353 (2016).
Lisboa-Filho, P. N. et al. Bone repair with raloxifene and bioglass nanoceramic composite in animal experiment. Connect. Res. 59, 97?101 (2018).
Bhowmick, A. et al. Development of bone-like zirconium oxide nanoceramic modified chitosan based porous nanocomposites for biomedical application. Int.J.Biol.Macromol. 95, 348?356 (2017).
Shokrollahi, H., Salimi, F. & Doostmohammadi, A. The fabrication and characterization of barium titanate/akermanite nano-bio-ceramic with a suitable piezoelectric coefficient for bone defect recovery. J.Mech.Behav.Biomed.Mater. 74, 365?370 (2017).


Download data is not yet available.
  • Views 193
  • Downloads 143
  • Citations 0
  • Shares 1
October 5, 2018
How to Cite
SINGH, Zorawar. Nanoceramics in Bone Tissue Engineering: The Future Lies Ahead. Trends Journal of Sciences Research, [S.l.], v. 3, n. 3, p. 120-123, oct. 2018. ISSN 2377-8083. Available at: <>. Date accessed: 21 july 2019.