Mohammad-Reza Nejadmoghaddam

Doctorate

Department of Recombinant Technology, Nanobiotechnology Research Center, Avicenna Research Institute, Shahid Beheshti University, Iran

Mohammad-Reza Nejadmoghaddam
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Outline

Education

2012-2018Ph.D. in Nanomedicine, From Nanotechnology Research Center, School of Pharmacy, Tehran university of Medical Sciences (TUMS)
2003-2006MSc in Molecular Microbiology, From Azad University1, Jahrom Branch
1995-1999BSc in Microbiology, From Azad University, Tonekabon Branch.
1990-1994Diploma in Experimental Sciences, GPA: 15.75/20.0., from Kosar High school in Tonekabon City, Mazandaran Province.

Research Interests

Antibody–drug conjugates (ADCs), as an innovative nanotherapeutics approach.

Nanomedicine in Diagnosis and Treatment of Hard to Treat Diseases.

Developing Simple and Inexpensive Protocols during a Research Project.

Molecular Biology and Nanotechnology Dramatic Advances in Biomolecule Purification and Nanomedicine preparation.

Memberships

Iranian Society of Immunology and Allergy, website: http://isiaonline.org/

Iranian Society of Nanomedicine, website: www.isnm.ir

Iranian Nano Technology Society, website: www.nanosociety-ir.com/

Iran Azad University young researchers club

Iranian Society for Biotechnology, website:

Publications

[1]
Mohammad-Reza Nejadmoghaddam, Amir-Hassan Zarnani, Mojtaba Mirhosseini Moghaddam, Fereshteh Mohammadi, Mohammad Eskandari, Ramin Ghahremanzadeh, Bioimaging based on the antibody-conjugated amphiphilic polymer-core@shell quantum dots, Emerging Materials Research, accepted, waiting to publish
[2]
Mohammad-Reza Nejadmoghaddam, Arash Minai-Tehrani, Ramin Ghahremanzadeh, Morteza Mahmoudi, Rassoul Dinarvand, Amir-hassan Zarnani; Antibody-Drug Conjugates: Possibilities and Challenges, Avicenna Journal of Medical Biotechnology (AJMB), Vol. 11, No. 1, January-March 2019
[3]
Mohammad-Reza Nejadmoghaddam, Amir-Hassan Zarnani, Ramin Ghahremanzadeh, Roya Ghods, Jafar Mahmoudian, Maryam Yousefi, Mahboobeh Nazari, Mohammad Hossein Ghahremani, Maryam Abolhasani, Ali Anissian, Morteza Mahmoudi, Rassoul Dinarvand; Placenta-specific1 (PLAC1) is a potential target for antibody-drug conjugate-based prostate cancer immunotherapy, Scientific reports, 2017/10/17, 7,1, 13373.
[4]
Mahboobeh Nazari, Amir-hassan Zarnani, Roya Ghods, Rahman Emamzadeh, Somayeh Najafzadeh, Arash Minai-Tehrani, Jafar Mahmoudian, Maryam Yousefi, Sedigheh Vafaei, Sam Massahi, Mohammad-Reza Nejadmoghaddam, Optimized protocol for soluble prokaryotic expression, purification and structural analysis of human placenta specific-1 (PLAC1), Protein Expression and Purification, 2017/5/31, 133, 139-151.
[5]
Zahra Rashid, Ramin Ghahremanzadeh, Mohammad-Reza Nejadmoghaddam, Mahboobeh Nazari, Mohammad-Reza Shokri, Hossein Naeimi, Amir-Hassan Zarnani, Nickel-Salen supported paramagnetic nanoparticles for 6-His-target recombinant protein affinity purification, Journal of Chromatography A, 2017/3/24, 1490, 47-53,
[6]
Mohammad-Reza Nejadmoghaddam, Abdolreza Babamahmoodi, Arash Minai-Tehrani,
[7]
Amir-Hassan Zarnani and Rassoul Dinarvand; The use of objective oriented project planning tools for nanosafety and health concerns: a case study in nanomedicine research project, European Journal of Nanomedicine, 2016 Agust,
[8]
Zahra Rashid, Hossein Naeimi, Amir-Hassan Zarnani, Mahboobeh Nazari, Mohammad-Reza Nejadmoghaddam, Ramin Ghahremanzadeh; Fast and highly efficient purification of 6× histidine-tagged recombinant proteins by Ni-decorated MnFe2O4@ SiO2@NH2@2AB as novel and efficient affinity adsorbent magnetic nanoparticles, RSC Advances, 2016, 6(43), 36840-36848
[9]
Sarah Niakan, Mohammad Niakan, Saeed Hesaraki, Mohammad Reza Nejadmoghaddam, Mohammad Moradi, Mojtaba Hanafiabdar, Roya Allamezadeh, Meysam Sabouri; Comparison of the Antibacterial Effects of Nanosilver with 18 Antibiotics on Multidrug Resistance Clinical Isolates of Acinetobacter baumannii, Jundishapur Journal of Microbiology. 2013 July ; 6(5): e8341
[10]
Mohammad Reza Nejadmoghaddam, Mahmood Chamankhah, Saeed Zarei, Amir Hassan Zarnani, Profiling and Quantitative Evaluation of Three Nickel-Coated Magnetic matrices for Purification of Recombinant Proteins: Helpful Hints for the Optimized Nanomagnetisable Matrix Preparation. Journal of Nanobiotechnology, 8 August 2011, 9:31
[11]
Mohsina Hamid, Khalil-Ur-Rehman and Mohammad Reza Nejaddmoqaddam. Investigation of Fibrinolytic Activity of Locally Produced Streptokinase, Asian Journal of Chemistry, Vol. 23, No. 1, 2011, 251-254.
[12]
Babashamsi M, Razavian MH and Nejadmoghaddam MR , Production and Purification of Streptokinase by Protected Affinity Chromatography, Avicenna Journal of Medical Biotechnology - A.J.M.B, 2009, 1 (1): 47-51
[13]
M.R. Nejadmoghaddam, M.H. Razaviyan, M. Babashamsi. Evaluation of Streptokinase Production Potential by Group C Streptococcal Strain H46A in Batch Culture and Bactericidal Effect of Hexyl Resorcinol, Journal of Babol University of Medical Sciences (JBUMS), 2009; 11 (4), 13-19,( Iranian Journal and in Persian language and an abstract in English Language)
[14]
Nejadmoghaddam MR., Hadavi R., Babashamsi M., Niakan M. Rapid and Efficient Escherichia coli Transformation Method. Daneshvar Medicine (Scientific-Research Journal of Shahed University), 2009; 16(80), 71-76. (Iranian Journal and in Persian language and an abstract in English Language)
[15]
Soleimani Rahbar AA, Niakan M, Fayaz F, Taheri S, Mahmoudian J, Nejadmoghaddam MR , Kolahi AA.,Crystal Violet in Culture Media for Diagnosis of Neisseria Species, Journal of the faculity of medicine (Shaheed Beheshti University of Medical Sciences and Health Services), 2008; 32(3), 201-206,
[16]
Nejadmoghaddam MR, Modarressi MH, Babashamsi M, Chamankhah M. (2007), Cloning and overexpression of active recombinant fusion streptokinase: a new approach to facilitate purification, Pak J Biol Sci., 10(13):2146-51, PMID: 19070173
[17]
Soheili M, Nejadmoghaddam MR, Babashamsi M, Ghasemi J, Jeddi Tehrani M. (2007), Detection of Legionella pneumophila by PCR-ELISA method in industrial cooling tower water, Pak J Biol Sci.,10(22):4015-21, PMID: 19090273
[18]
Nejadmoghaddam, MR; Modaresi, MH; Babashamsi, M; Chamankhah, M; 2006. Streptokinase: Extraction, Cloning and Active recombinant protein overexpression, with Facilitate approach in purification. Journal of the faculity of medicine (Shaheed Beheshti University of Medical Sciences and Health Services), Vol. 30, No.3, p. 245-252. (Iranian Journal and in Persian language and an abstract in English Language)
[19]
Nejadmoqaddam, MR 2005, Topic parameters for PCR Optimization, Iranian Students Book agency (ISBA), Tehran. ISBA Web addresses site: http://www.isba.ir/Book/asp/Book_Detail.asp?BID=2159 (In Persian language)
[20]
Niakan, M; Forotan, SK; Fallah, N; Shafee, M; Sedighi, MA; Nejadmoghaddam, MR; Mansouri, S; Detection the Frequency of M.hominis in Infertile Men '' Abnormal Semen'' with Control Group, Daneshvar (Scientific-Research Journal of Shahed University), 2005; 12(56), 65-70. (Iranian Journal and in Persian language and an abstract in English Language).
[21]
Mohammad-Reza Nejadmoghaddam, Rassoul Dinarvand, Ramin Ghahremanzadeh, Roya Ghods, Jafar Mahmoudian, MaryamYousef, Mahboobeh Nazari, Mohammad Hossein Ghahremani, Maryam Abolhasani, Ali Anissian, Morteza Mahmoudi & Amir-Hassan Zarnani., Introduction of the First Antibody Drug Conjugate (ADC) based on anti- Placenta-specific1 (PLAC1) Antibody as a Novel Immunotherapeutic Tool for Prostate Cancer, 14th international congress of Immunology and Allergy, 26-28 April 2018, Tehran, I.R..Iran
[22]
Mohammad Reza Nejadmoghaddam, The role of team thinking for success on the responsibility with the lowest authority, Iran High-Tech Laboratory Network Meeting, September 9, 2015.,
[23]
Mohammad Reza Nejadmoghaddam and Rassoul Dinarvand, Antibody Drug Conjugates as novel tumor-targeted nanomedicine, Proceeding of the National Conference on Nanomedicine in Diagnosis and Treatment of Hard to Treat Diseases, 18-19 Februar, 2015, p 50-51 , Avicenna Research Institute, Tehran, Iran.
[24]
Mohammad Reza Nejadmoghaddam, Amir Hassan Zarnani, Roya Ghods,Mohammad Hossein Ghahremani, Rassoul Dinarvand, Targeted Delivery Nanomedicine against Prostate Cancer Cell Lines Based on Antibody Drug Conjugates, Proceeding of the National Conference on Nanomedicine in Diagnosis and Treatment of Hard to Treat Diseases, 18-19 Februar, 2015, p 280-281 , Avicenna Research Institute, Tehran, Iran.
[25]
Nejadmoghaddam MR, Cytotoxic agent (drug) Criteria to use in Antibody Drug Conjugates (ADCs), Annual scientific lectures in Avicenna Research Institute, Shahid Beheshti University, Evin, Tehran, Iran, Novamber15, 2014.,
[26]
Nejadmoghaddam MR, Antibody-Drug Conjugates (ADCs): Homing Cytotoxic Agents in tumor cells using Conjugation to Antibodies, Annual scientific lectures in Avicenna Research Institute, Shahid Beheshti University, Evin, Tehran, Iran, May 19, 2014.,
[27]
Nejadmoghaddam MR, Team working for successful Project Management , Annual scientific lectures in Avicenna Research Institute, Shahid Beheshti University, Evin, Tehran, Iran, December 9, 2013.,
[28]
Nejadmoghaddam MR, Novel Magnetisable Protein Purification Systems: Topic Parameters for Magnetisable Solid Phase Support preparation, Annual scientific lectures in Avicenna Research Institute, Shahid Beheshti University, Evin, Tehran, Iran, February 14, 2011, http://www.avicenna.ac.ir/index.php/fa/education/cme/journal-clubs
[29]
M.R. Nejadmoghaddam, M. Chamankhah, Extraction and Purification of Nanomagnetic Particles from Magnetic Bacteria, 3rd International Congress on Nanoscience and Nanotechnology (ICNN 2010), 9-11 November 2010, Shiraz University, Shiraz, I.R.Iran
[30]
Nejadmoghaddam MR, Protein Purification using magnetic particles, Annual scientific lectures in Avicenna Research Institute, Shahid Beheshti University, Evin, Tehran, Iran,, December 28, 2009., http://www.avicenna.ac.ir/index.php/fa/education/cme/journal-clubs
[31]
Nejadmoghaddam M.R., Chamankhah M; Optimization of magnetic affinity separation method for highly-efficient purification of polyhistidine-tagged proteins, 7th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, 20-24 May 2008, Vancouver, Canada
[32]
Nejadmoghaddam MR, Magnetotactic Bacteria: Potential Applications in Nanobiotechnology, Annual scientific lectures in Avicenna Research Institute, Shahid Beheshti University, Evin, Tehran, Iran, February 25, 2008., http://www.avicenna.ac.ir/index.php/fa/education/cme/journal-clubs
[33]
Nejadmoqaddam, M.R; Hadavi, R; Babashams, M; Niakan, M; The Improvement of the Competent cell Preparation Method and E. coli High Efficiency Genetic Transformation, 1st International Congress on Health Genomics and Biotechnology, 24-26 Nov, 2007, Summit meeting Conference Hall, Tehran, Iran; Iranian Biomedical Journal, Vol. 11, Supp. 1.
[34]
Nejadmoqaddam, M.R; Babashamsi, M; Modaresi, M.H; Molecular Cloning and Expression Fusion Streptokinase for easy Purification, International Conference on Biotechnology Engineering (ICBioE '07), Proceeding of the International Conference on Biotechnology Engineering (ICBioE '07), ISBN: 978-983-43090-2-2, may 8-10, 2007, Kuala Lumpur, Malaysia, P:1-10.
[35]
Nejadmoghaddam MR, herpes simplex virus,human sperm and assisted reproduction technology, Annual scientific lectures in Avicenna Research Institute, Shahid Beheshti University, Evin, Tehran, Iran,, July 24, 2006., http://www.avicenna.ac.ir/index.php/fa/education/cme/journal-clubs
[36]
Babashamsi, M; Nejadmoghaddam, M.R; Modaresi, MH; Production, purification and assay of native and recombinant streptokinase. 10th Iranian Pharmaceutical Sciences Conference (IPSC 2006)21-24 August 2006, Published in Iranian Journal of Pharmaceutical Sciences, 2006, Vol. 2, No. 3: 282.
[37]
Nejadmoghaddam MR; Niakan M; Hoseini SM., Ghahremanzadeh K, Prevalence of mycolasma hominis and ureaplasma urealyticom in infertile females of Tehran infertility clinics, 15th Iranian Congress on Infectous Disease and Tropical Medicine, 16-20 December 2006, Tehran in The Ministry of Foreign Affairs Instituted for Political and International Studies, Iran, pp.42.
[38]
Araghi, Sh; Nejadmoghaddam, MR; Modaresi, MH; Babashamsi, M; Amirmozaffari, N; Extraction and cloning of mutant streptokinase gene in order to reduce its immunogenicity, 14th National and 2nd International Conference of Biology, 29-31 Aug 2006,Tarbiat Modarres University, Tehran, Iran. p. 393.
[39]
Negadmoqaddam, MR; Moddaressi,MH; Babashamsi, M; Extraction and cloning of streptokinase gene with simplify purification approach, 4th national biotechnology congress Islamic Republic of Iran,15-17 Aug 2005,Kerman, Kerman, Iran. p. 330.
[40]
Nejadmoghaddam, MR; Chamankhah, M; Abasiyan, F; Designing of biological motors in Nanobiotechnology, The 4rd National congress of Basic Science, 7-8 Dec 2005,Dezful Azad University,Khozestan,Iran.
[41]
Nejadmoghaddam, MR; Kafilzadeh, F; Bioindicator recommendation for ecosystem assesment, 1st Student conference of Biotechnology, 15-7 Nov 2005, Tehran University,Tehran,Iran. p. 122.
[42]
Nejadmoghaddam,MR; Babashamsi, MM;Razavian, H; Optimization of streptococcus β-hemolyticus group-C batch culture and evaluation of it's potency for production of streptokinase and bacteriocidal effect of hexyl resorcinol, 6th Iranian Congress of Microbiology I.R.Iran, 16-18 Feb 2004,Tehran, Tehran Emam Khomeini Hospital,Tehran,Iran. p. 20.
[43]
Babashamsi, M; Razavian MH; Nejadmoghaddam, MR; Optimization of streptokinase secretion and its rapid purification, 7th Iranian Congress of Biochemistry, 11-15 Sep 2004, Ahvaz, Khozestan, Iran. pp. 112.
[44]
Babashamsi, M; Razavian, MH; Nejadmoghaddam, MR; Production and purification of streptokinase by protected affinity chromatography, Saudi Bio-2004 International Conference, 10-11 May 2004, Jeddah, Kigdom of Saudi Arabia.
[45]
Razavian, MH; Babashamsi, M; Nejadmoghaddam, MR; A single step purification of plasminogen from human plasma, 3rd National Congress of Biotechnology, 9-11 Sep 2003, Ferdowsi University of Mashhad, Khorasan, Iran. Pp. 241-243.
[46]
Nejadmoghaddam, MR; Niakan, M; Babashamsi, M, Prevalence of mycolasma hominis and ureaplasma urealyticom in infertile females of Tehran infertile, 10th Annual scientific meeting Anniversary Middle Erast fertility saietl, 10-13 December 2003, Phoenicio Sntercontinental, Beirut, Lebanon.
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46 Publications

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